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Semaglutide Weight Loss Guide: Everything You Need to Know

Semaglutide Weight Loss Guide: Everything You Need to Know

Used by 920,000 patients to lose 26%+ Bodyweight

Used by 920,000 patients to lose 26%+ weight

Minimal effort - Maximum Results

Clinically proven weight loss (Pharmacist guided)

"Down 9kg in the last month. Finally fit into those jeans I've kept tucked away for years!! I'm down 2 dress sizes in my favourite shop - love the product and the ongoing support"

— Jane Lianee Cheltenham (Age 37)

New Patient Welcome Package:

New Patient Welcome Package:

Weight Loss Consultation

£50

FREE

One hour consultation with our professional and highly trained weight loss inj experts

Weight Loss Consultation

£50

FREE

One hour consultation with our professional and highly trained weight loss inj experts

Weight Loss Consultation

£50

FREE

One hour consultation with our professional and highly trained weight loss inj experts

Initial Weight Loss Treatment

£225

£137

Weight Loss Inj Treatment

Initial Weight Loss Treatment

£225

£137

Weight Loss Inj Treatment

Initial Weight Loss Treatment

£225

£137

Weight Loss Inj Treatment

Weight Loss Aftercare & Support

£50

FREE

Dedicated follow-up support with the highest expertise of weight loss inj

Weight Loss Aftercare & Support

£50

FREE

Dedicated follow-up support with the highest expertise of weight loss inj

Weight Loss Aftercare & Support

£50

FREE

Dedicated follow-up support with the highest expertise of weight loss inj

Total

£325

£137

Total

£325

£137

Total

£325

£137

5 Spots left this week (max capacity)

5 Spots left this week (max capacity)

Semaglutide Weight Loss Guide — Complete Overview for Gloucestershire Patients

Looking for a medically-proven solution to help lose weight and keep it off? Semaglutide, the active ingredient behind Wegovy and Ozempic, is quickly becoming one of the most effective weight loss injections in the UK. Whether you’ve struggled with dieting, appetite control, or weight gain due to hormones, Semaglutide may be the breakthrough you're looking for.

At Gloucestershire Pharmacy & Clinic, 305 High St, Cheltenham GL50 3HW, we provide fully supported Semaglutide treatment plans. Call 01242 437910 or book your consultation online to get started today.

What Is Semaglutide?

Semaglutide is a GLP-1 receptor agonist, originally developed for diabetes but now widely used for weight loss. It mimics a natural gut hormone that regulates appetite and insulin. Brands like Wegovy and Ozempic are powered by semaglutide but are prescribed for different reasons—weight loss vs diabetes.

How Semaglutide Aids Weight Loss

  • Suppresses appetite by slowing gastric emptying

  • Reduces cravings and emotional eating

  • Improves insulin sensitivity, reducing fat storage

  • Helps achieve a calorie deficit without intense hunger

These effects contribute to average weight loss of 10–15% body weight in clinical studies.

Semaglutide Injection for Weight Loss

Semaglutide is injected once per week subcutaneously. The most common format is a prefilled pen, designed for easy at-home use. Our clinic provides injection demonstrations and in-clinic support if needed.

Semaglutide Available in the UK

Semaglutide is MHRA-approved for weight loss under the brand Wegovy. It’s available:

  • Privately at specialist clinics like ours

  • NHS only for select patients in Tier 3 or Tier 4 obesity programmes

Explore NHS eligibility at the England NHS obesity medicines page.

Semaglutide for Weight Loss in Non-Diabetics Dosage

Yes—Semaglutide is often prescribed to non-diabetics with a BMI ≥27 and weight-related health issues. The starting dose is typically 0.25 mg weekly, gradually increasing to 2.4 mg over several weeks.

Semaglutide Injection Side Effects

Common side effects include:

  • Nausea

  • Diarrhoea

  • Constipation

  • Bloating

Less common:

  • Headaches

  • Heartburn

  • Dizziness

Rare risks: pancreatitis or gallbladder issues. Let our clinic know if you experience persistent symptoms.

Semaglutide Side Effects UK

UK-specific side effect data aligns with MHRA guidance. Always report unusual reactions via the Yellow Card Scheme or directly with your healthcare provider.

Semaglutide Before and After

Patients at our Cheltenham weight loss clinic often see:

  • 3–5 kg lost in the first month

  • Waistline reduction

  • Improved energy and mood

  • Better portion control

View more at our Mounjaro article for comparison.

Semaglutide Doses & Dosage Chart

Week Range

Weekly Dose

Weeks 1–4

0.25 mg

Weeks 5–8

0.5 mg

Weeks 9–12

1.0 mg

Weeks 13–16

1.7 mg

Week 17+

2.4 mg

We monitor and adjust based on your tolerance and progress.

Semaglutide Cost & Injection Price

At Gloucestershire Pharmacy & Clinic, Semaglutide costs range between:

  • £137–£250 per month, depending on dosage
    This includes consultations, prescription, and lifestyle support. Learn more at weightlossclinic.

Semaglutide Pen, Vial & Nasal Spray Options

  • Pen: Most popular, easy-to-use, prefilled

  • Vial: Rare in the UK—requires syringes and preparation

  • Nasal spray: In clinical trials, not yet approved in the UK

We prescribe semaglutide pens with local training and safe handling.

Semaglutide vs Ozempic

Same molecule, but:

  • Ozempic = 1.0 mg max, for diabetes

  • Semaglutide/Wegovy = 2.4 mg max, for weight loss

Wegovy uses higher doses proven to reduce body weight in clinical trials.

Semaglutide vs Mounjaro

  • Semaglutide: GLP-1 only

  • Mounjaro: GLP-1 + GIP dual agonist

Mounjaro may produce more dramatic results, but also more side effects. Learn more in our Mounjaro guide.

Semaglutide vs Wegovy

Technically the same drug—Wegovy is the branded weight loss version of Semaglutide at higher doses. Learn more in our full Wegovy guide.

Semaglutide BNF Info

In the British National Formulary (BNF), semaglutide is listed under GLP‑1 analogues for diabetes, with emerging recognition in weight management. Always use under clinician supervision.

Why Choose Gloucestershire Pharmacy & Clinic

  • Local care with Cheltenham weight loss experts

  • Access to Semaglutide injections near me

  • Personalized advice, dose tracking, and dietary support

  • Fast prescriptions with no online delays

Learn more about our weight loss treatments.

Semaglutide Meal Tips & Lifestyle Integration

To get the most from Semaglutide:

  • Eat protein at every meal

  • Avoid greasy or fried foods

  • Stay hydrated

  • Exercise moderately 3–4 times per week

Patient Success Stories & Testimonials

“After 6 months on Semaglutide at this clinic, I’ve lost 18 kg and feel healthier than ever. The weekly check-ins and support made all the difference.”
Ellie M., Cheltenham

Booking & Clinic Info

Address: 305 High St, Cheltenham GL50 3HW
Phone: 01242 437910
Hours: Mon–Fri 9 am–6 pm | Sat–Sun: Closed

Book your consultation here

FAQs

Can I use Semaglutide if I’m not diabetic?
Yes—Wegovy (semaglutide) is approved for non-diabetic weight loss.

Is it safe to switch from Mounjaro to Semaglutide?
Yes. Read our guide on how to switch.

Do I need a prescription?
Yes. We provide in-house private prescriptions.

Is the injection painful?
Most patients report minimal discomfort. Pens use ultra-thin needles.

Conclusion

Semaglutide offers a science-backed, doctor-supported approach to sustained fat loss. At Gloucestershire Pharmacy & Clinic, we combine trusted medication with personalised care, helping you lose weight safely.

📞 Call 01242 437910 or book online now to begin your weight loss journey with confidence.

References & Further Reading

Curated and Written By Clinic Experts

Curated and Written By Clinic Experts

Gloucestershire's Pharma Clinician combines unmatched expertise with hands-on clinical excellence—bringing the region’s most comprehensive knowledge base under one roof.

Tufael

Lead Pharma Clinician

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Lead Pharma Clinician

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Lead Pharma Clinician

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5 Stars ★★★★★

"Tufael supported me throughout my entire journey, giving me the confidence not just to take the leap but to feel reassured during every call and check-in. We reviewed everything—my weight, dress sizes, how I was feeling, any side effects, and my general well-being—so I always felt in safe hands. This is why I trust a real clinic over online distributors."

"Tufael supported me throughout my entire journey, giving me the confidence not just to take the leap but to feel reassured during every call and check-in. We reviewed everything—my weight, dress sizes, how I was feeling, any side effects, and my general well-being—so I always felt in safe hands. This is why I trust a real clinic over online distributors."

— Sandra Heart 47 Cheltenham

New Patients Welcome Package:

New Patients Welcome Package:

[SUMMER100] for New Patients Open Now for Limited Capacity

[SUMMER100] for New Patients Open Now for Limited Capacity

Gloucestershire Weight Loss Mounjaro
Gloucestershire Weight Loss Mounjaro

Weight Loss Consultation

£50

FREE

One hour consultation with our professional and highly trained weight loss inj experts

Weight Loss Consultation

£50

FREE

One hour consultation with our professional and highly trained weight loss inj experts

Weight Loss Consultation

£50

FREE

One hour consultation with our professional and highly trained weight loss inj experts

Initial Weight Loss Treatment

£225

£137

Weight Loss Inj Treatment

Initial Weight Loss Treatment

£225

£137

Weight Loss Inj Treatment

Initial Weight Loss Treatment

£225

£137

Weight Loss Inj Treatment

Weight Loss Aftercare & Support

£50

FREE

Dedicated follow-up support with the highest expertise of weight loss inj

Weight Loss Aftercare & Support

£50

FREE

Dedicated follow-up support with the highest expertise of weight loss inj

Weight Loss Aftercare & Support

£50

FREE

Dedicated follow-up support with the highest expertise of weight loss inj

Total

£325

£137

Total

£325

£137

Total

£325

£137

5 Spots left this week (max capacity)

5 Spots left this week (max capacity)